The four remaining candidates for the Republican presidential nomination appeared yesterday in a last-ditch debate before Saturday's South Carolina primary. The debate got off to a dramatic start with contender Newt Gingrich attacking CNN host John King for opening with a question about his personal life.

Rick Perry is out, Rick Santorum actually won Iowa, and Newt Gingrich's second wife says he asked for an open marriage before he filed for divorce. The four remaining candidates debated in Charleston one last time before this weekend's South Carolina primary. We take a look back at what was arguably the wildest day of the 2012 Presidential campaign thus far.

The Diagnostic Statistical Manual (DSM) is a dictionary that defines and classifies all mental health disorders. First published in 1952, the DSM is used by everyone from clinicians to pharmaceutical companies to policy makers. Since its inception, the DSM has been revised only four times — one such occasion was in 1980 when homosexuality was no longer defined as a mental disorder. In the fifth edition, another big change may come to the DSM. Autism is up for a redefinition which could potentially reduce the number of people considered "autistic" by half.

Steven Soderbergh is a director who is not afraid to try new things. His films range from a remake of the popular rat pack vehicle "Ocean’s Eleven" to the multi-part biopic “Che” to his experimental film "Scizopolis." On Friday his latest risky endeavor, "Haywire," hits theaters. Newcomer Gina Carano stars as a mixed martial arts fighter who seeks revenge after being betrayed during a mission.

Megaupload, one of the internet's largest file-sharing sites, has been shut down by officials in the U.S. Federal prosecutors claim the site has cost copyright holders more than $ 500 million in lost revenue — a claim Megaupload denies.

With Texas Governor Rick Perry dropping out of the race and Rick Santorum declaring a belated victory in the Iowa caucuses, Thursday marked a day of big game changers in the GOP presidential contest. With one day left until the South Carolina primary, frontrunner Mitt Romney is slipping in the polls as Gingrich picks up more support, including an endorsement from Perry. As the Republican race gets tighter and attacks become even more brutal, how is President Barack Obama preparing for his campaign for 2012? 

Considering Kodak's recent financial woes, the imaging giant's Chapter 11 filing should have come as no surprise. But that hasn't lessened the cultural impact of losing such an iconic American institution. Kodak has been a part of American culture for more than a 100 years. The company made the first consumer camera, and people even called cameras "Kodaks" at the turn of the century. In this commentary we explore the rise and fall of one of America's most identifiable brands.

Friday South Carolina will hold the "First in the South" primary. Since 1980 the victor of the South Carolina primary has gone on to win the presidential nomination. But the Palmetto State is sharing the limelight this morning with the Hawkeye State as the miscount in Iowa has skewed the results of the first GOP caucus. Rick Santorum is now declared the winner of the Iowa Caucus by a small margin of 34 votes. But in the end does it really matter?

While we are distracted by the circus of the GOP political race, the war continues in Afghanistan, and we have several tragic stories out of that country this morning. A NATO helicopter crashed in Afghanistan last night killing six service members. The cause is still being investigated. Also this morning. An Afghan soldier shot and killed four French troops, leading French President Nicolas Sarkozy to suspend its training programs in Afghanistan. Matt Rosenberg is a reporter for our partner The New York Times.

Wyatt Cenac is best known as "The Daily Show" correspondent behind popular segments like "Black to the Future" and "Rapper or Republican." When he is not working for "The Daily Show," Cenac’s is acting and performing as a stand-up comedian. His current project, hosting the fourth season of "AfroPoP: The Ultimate Cultural Exchange," is a documentary series profiling men and women from across the African Diaspora — including California punk band Fishbone, a 26-year-old solar energy entrepreneur in Mali, and a minister’s daughter who plays calypso music.

Megaupload.com one of the world's most popular file-sharing sites was shut down yesterday on charges that it illegally shared movies, TV shows, and e-books. A federal indictment accuses the company of costing copyright holders at least $500 million in lost revenue. In retaliation hacker groups went after several Web sites including those of the Justice Department and Universal. Ira Rothken is a lawyer for Megaupload.com.