After nearly 30 years of stony diplomatic silence, Iran and the U.S. sat down together at a negotiating table early today. Six countries are attending the meetings in Geneva to talk to Iranian representatives about the country's nuclear program. U.S. representatives are sharing the table with Britain, France, Germany, China and Russia, but reports yesterday evening suggest the U.S. could meet one-on-one with Iran. We preview the talks and look at the pros and cons of imposing more sanctions.

We speak with John Limbert, author of "Negotiating With Iran: Wrestling the Ghosts of History." He was an American diplomat in Tehran during the Iranian Revolution, and was held hostage for over a year during that time. We also speak to George Lopez, a sanctions expert and senior fellow at the University of Notre Dame; and Mark Landler, diplomatic correspondent for The New York Times.

Takeaway Washington correspondent Todd Zwillich joins us to talk about a new climate bill introduced by two Democratic Senators: Barbara Boxer, of California; and John Kerry, of Massachusetts.

New York Times finance reporter Louise Story joins us to talk about Bank of America's chief executive, Kenneth Lewis, stepping down.

Yesterday we asked how often people do things like texting and talking on the phone while driving. Listeners weighed in all day, suggesting solutions to combat DWD ("Driving While Distracted") and responding to 19-year-old Alicia Jones, who admitted on the air yesterday to texting while driving.

A second earthquake struck Indonesia last night. This follows yesterday's devastating quake that has killed over 500 people, many trapped under collapsed buildings. The death toll is expected to climb further. The BBC's Karishma Vaswani joins us again from Padang, capital of West Sumatra, which is the nearest city to the earthquake's epicenter.

General Motors announced yesterday that it will shut down its Saturn subsidiary. The 24-year-old brand appeared close to being saved under a deal with former race car driver and Detroit business man Roger Penske, but the deal collapsed at the last minute. We speak to Micki Maynard, business reporter for The New York Times.

President Obama is in Copenhagen today to make the case that Chicago should be the host city for the 2016 Summer Olympics. We measure the mood in Denmark with BBC Sports News correspondent Alex Capstick.

And we're asking you, Is the president spending his international political capital on the right issue?

As Washington debates whether or not to send more troops to help stabilize Afghanistan, big questions remain about the strength and legitimacy of the Afghan government. President Karzai has defended himself and the integrity of the country's electoral process against allegations of fraud in the country's second-ever presidential election. Presently Karzai has 54.6 percent of the vote, well ahead of his leading challenger, Abdullah Abdullah. The ongoing recounts and fraud investigations by the Election Complaints Commission, however, could drive Karzai's total below the crucial 50 percent, forcing a runoff election. To find out more about the relationship between the U.S. and the Karzai administration, we speak with Zalmay Khalilzad, the Afghan-born former U.S. Ambassador to Agfhanistan. He currently runs his own consultancy firm called Khalilzad Associates. (Click through for the full interview transcript.)

[An abridged version of the Google Wave presentation that went viral earlier this year.]

Google is making an ambitious play with a new web application. They say their new tool, Google Wave, is what email might look like if it were invented today. With one tool, they're trying to create a single replacement for email, instant messaging and document sharing. We talk with Gina Trapani, editor of Life Hacker; and Sree Sreenivasan, Columbia University digital journalism professor, about whether Google's success is going to its head and whether Microsoft might finally be making a comeback with the Bing search engine.

The International Monetary Fund says the global recession is ending. In its twice-yearly assessment of the economic outlook for the world, the IMF predicts a 3.1 percent global economic growth rate. We talk with the BBC’s economics correspondent, Andrew Walker.

Yesterday we got a perspective on the health care debate from three Democratic lawmakers who are also health care professionals. Today we hear from three Republicans in Congress who are also doctors. We ask why they don’t want the government much involved in health care. We are joined by two Congressmen: Dr. Charles Boustany (R-La.), who has 20 years of experience as a cardiovascular surgeon; and Dr. Michael Burgess (R-Tex.), who practiced obstetrics and gynecology for over 20 years before running for office. We're also joined by Dr. John Barrasso, Republican senator from Wyoming; he has been an orthopedic surgeon for nearly 25 years...(click through for the full interview transcript)

Takeaway Washington correspondent Todd Zwillich joins us to talk about the latest in health care reform and the fight between Republicans and Democrats over troop levels in Afghanistan.

One of the largest lenders in the country to small businesses, CIT Group, may be headed for collapse. CIT is working to present restructuring plans to federal regulators by the end of today. New York Times finance reporter Louise Story joins us with the details.

Takeaway sports contributor Ibrahim Abdul-Matin joins us to talk about the MLB as the regular season winds down and the NHL as the 2009 season starts up.

Peter Galbraith, the highest-ranking American working for the U.N. mission in Afghanistan, is losing his job, allegedly for raising too many concerns about accusations of fraud in the recent Afghan presidential elections. He joins The Takeaway to discuss his side of the story ... and what more he thinks the U.N. could be doing to clean up elections there. (click through for the full interview transcript.)

At the beginning of his presidency, Bill Clinton spent hours in private, secret interviews with close friend and Pulitzer prize–winning journalist Taylor Branch. They talked about Monca Lewinsky and the Oklahoma City bombings; they dished about world leaders and soon-to-be president George W. Bush. Now, after years, Branch has amassed his own musings about the talks into a more than 700-page tome. We ask him about his book, "The Clinton Tapes: Wrestling History With the President."

(click through to read the first chapter of "The Clinton Tapes")