Following the announcement that senator Ted Kennedy has a brain tumor, we talk with On Point's Jack Beatty, a longtime observer of Massachusetts politics.

Anti-immigrant attacks have led to 22 deaths and the displacement of 13,000 people in Johannesburg, South Africa. The Takeaway talks with a professor and a migrant in South Africa as violence escalates.

Chicago residents are now paying the highest gas prices in the country - an average of $4.07 per gallon. You might think that gas stations are thriving with high gas prices, but gas station owners are actually losing money.

In Chicago, some pumps are charging nearly $4.50 a gallon, while in Texas, residents are getting a relative bargain, paying a wee $3.53 at some stations. The Takeaway asks what are the forces behind these regional variations. Economist Robert Pindyck thinks he has the answer.

News of Ted Kennedy's brain tumor sent shockwaves across Washington ... where he has served as the senator from Massachusetts for more than 45 years. Kevin Cullen, columnist for the Boston Globe, says that for many people in Massachusetts this might signal the end of an era.

Guest: David Axelrod, Obama campaign chief strategist.